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Human EDNRB Stable Cell Line-CHO
Endothelins are a family of vasoactive peptides that includes ET-1, ET-2 and ET-3. To date, two subtypes of endothelin receptors have been identified from mammalian cells, EDNRA (ETA) and EDNRB (ETB). The EDNRA receptors have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The EDNRB receptors bind ET-1, ET-2 and ET-3 with nearly equal affinity and are expressed abundantly in endothelial cells and epithelial tissues. Although the vasoconstrictor and proliferative effects of ET-1 are primarily mediated by EDNRA receptors, EDNRB receptors can also mediate the vasoconstrictor response through ET-1-induced nitric oxide release from endothelial cells.
| Product Information | |
|---|---|
| Catalog #: | ACC-RG0840 |
| Gene Name: | EDNRB |
| Abbr | CHO-HuEDNRB |
| Alias | EDNRB,HSCR,HSCR2,ETB,ET-B,ETBR,ETRB,HSCR,WS4A,ABCDS,ET-BR,HSCR2 |
| Growth Properties | Adherent |
| Host Cell | CHO-K1 |
| Morphology | Epithelial-like |
| Product Format | frozen |
| Product Type | GPCR Expressing Cell |
| searchKeyword | EDNRB,HSCR,HSCR2,ETB,ET-B,ETBR,ETRB,HSCR,WS4A,ABCDS,ET-BR,HSCR2 |
| Shipping | Dry ice |
| Species | Human |
| Stability | 12 passages of continuous culture (6 weeks) at 2 passages/week |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RG1730 | Human EDNRB Stable Cell Line-CHO-K1 | EDNRB | Human | INQUIRY | |
| ACC-RG0021 | Human EDNRB Stable Cell Line-U2OS | EDNRB | Human | Epithelial | INQUIRY |
| ACC-RG0048 | Human EDNRB-SNAP Stable Cell Line-HEK293 | EDNRB | Human | Epithelial | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
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