Endothelins are a family of vasoactive peptides that includes ET-1, ET-2 and ET-3. To date, two subtypes of endothelin receptors have been identified from mammalian cells, EDNRA (ETA) and EDNRB (ETB). The EDNRA receptors have a much greater affinity for ET-1 over ET-3 and are expressed abundantly in vascular smooth muscles and stromal tissues. The EDNRB receptors bind ET-1, ET-2 and ET-3 with nearly equal affinity and are expressed abundantly in endothelial cells and epithelial tissues. Although the vasoconstrictor and proliferative effects of ET-1 are primarily mediated by EDNRA receptors, EDNRB receptors can also mediate the vasoconstrictor response through ET-1-induced nitric oxide release from endothelial cells.

Product Information
Catalog #:	ACC-RG0840
Gene Name	EDNRB
Abbr	CHO-HuEDNRB
Alias	EDNRB,HSCR,HSCR2,ETB,ET-B,ETBR,ETRB,HSCR,WS4A,ABCDS,ET-BR,HSCR2
Growth Properties	Adherent
Host Cell	CHO-K1
Morphology	Epithelial-like
Shipping	Dry ice
Product Type	GPCR Expressing Cell
Species	Human
Stability	12 passages of continuous culture (6 weeks) at 2 passages/week
Product Format	frozen
searchKeyword	EDNRB,HSCR,HSCR2,ETB,ET-B,ETBR,ETRB,HSCR,WS4A,ABCDS,ET-BR,HSCR2

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RG1730	Human EDNRB Stable Cell Line-CHO-K1	EDNRB	Human		INQUIRY
ACC-RG0021	Human EDNRB Stable Cell Line-U2OS	EDNRB	Human	Epithelial	INQUIRY
ACC-RG0656	Human EDNRB/Galpha15 Stable Cell Line-CHO	EDNRB	Human	Epithelial-like	INQUIRY
ACC-RG1275	Human EDNRB/Apoaequorin Stable Cell Line-CHO	EDNRB	Human	Epithelial-like	INQUIRY
ACC-RG0048	Human EDNRB-SNAP Stable Cell Line-HEK293	EDNRB	Human	Epithelial	INQUIRY