- Home
-
Screening
- Ionic Screening Service
-
Ionic Screening Panel
- Ligand Gated Ion Channels
- Glycine Receptors
- 5-HT Receptors3
- Nicotinic Acetylcholine Receptors
- Ionotropic Glutamate-gated Receptors
- GABAa Receptors
- Cystic Fibrosis Transmembrane Conductance Regulators (CFTR)
- ATP gated P2X Channels
- Voltage-Gated Ion Channels
- Calcium Channels
- Chloride Channels
- Potassium Channels
- Sodium Channels
- ASICs
- TRP Channels
- Other Ion Channels
- Stable Cell Lines
- Cardiology
- Neurology
- Ophthalmology
-
Platform
-
Experiment Systems
- Xenopus Oocyte Screening Model
- Acute Isolated Cardiomyocytes
- Acute Dissociated Neurons
- Primary Cultured Neurons
- Cultured Neuronal Cell Lines
- iPSC-derived Cardiomyocytes/Neurons
- Acute/Cultured Organotypic Brain Slices
- Oxygen Glucose Deprivation Model
- 3D Cell Culture
- iPSC-derived Neurons
- Isolation and culture of neural stem/progenitor cells
- Animal Models
- Techinques
- Resource
- Equipment
-
Experiment Systems
- Order
- Careers
Human CACNA1A/AP4B1/CACNA2D1/KCNJ2 Stable Cell Line-HEK293
The human CACNA1A gene encodes the pore-forming subunit of Cav2.1, the voltage-gated P/Q-type calcium channel. Inclusion of auxiliary subunits modulate gating and pharmacological characteristics, while the inwardly rectifying potassium channel allows the membrane potential to be altered with changes in extracellular K+. Mutations in CACNA1A are responsible for several inherited neurologic disorders including, familial hemiplegic migraine, episodic ataxia type2, and spinocerebellar ataxia type 6 epilepsy. Cav2.1 channels expressed in neurons are therapeutic targets in pain.
| Product Information | |
|---|---|
| Catalog #: | ACC-RI0072 |
| Gene Name: | KCNJ2 |
| Abbr | HEK293-HuCACNA1A/AP4B1/CACNA2D1/KCNJ2 |
| Alias | KCNJ2,IRK1,Kir2.1,IRK-1,hIRK1,LQT7,SQT3,ATFB9,HHIRK1,KIR2.1,HHBIRK1 |
| Channel Subgroup | Inwardly rectifying (Kir) |
| Channel Type | Potassium Channel |
| Growth Properties | Adherent |
| Host Cell | HEK293 |
| Morphology | Epithelial |
| Product Format | frozen |
| Product Type | Ion Channel Expressing Cell |
| searchKeyword | KCNJ2,IRK1,Kir2.1,IRK-1,hIRK1,LQT7,SQT3,ATFB9,HHIRK1,KIR2.1,HHBIRK1 |
| Shipping | Dry ice |
| Species | Human |
Related Products
| Catalog | Product Name | Gene Name | Species | Morphology | Price |
|---|---|---|---|---|---|
| ACC-RI0024 | Human KCNJ2 Stable Cell Line-HEK293 | KCNJ2 | Human | Epithelial | INQUIRY |
| ACC-RI0074 | Human CACNA1B/BHLHE22/CACNA2D1/KCNJ2 Stable Cell Line-HEK293 | KCNJ2 | Human | Epithelial | INQUIRY |
| ACC-RI0080 | Human CACNA1H/CACNB2/CACNA2D1/KCNJ2 Stable Cell Line-HEK293 | KCNJ2 | Human | Epithelial | INQUIRY |
| ACC-RI0116 | Human KCNJ2 Stable Cell Line-CHO | KCNJ2 | Human | Epithelial-like | INQUIRY |
| ACC-RI0115 | Human KCNJ2 Stable Cell Line-HEK293 | KCNJ2 | Human | Epithelial | INQUIRY |
| ACC-RI0070 | Human CACNA1D/CACNB3/CACNA2D1 + KCNJ2(tetracycline-inducible) Stable Cell Line-HEK293 | KCNJ2 | Human | Epithelial | INQUIRY |
| ACC-RI0066 | Human CACNA1C/NEUROD1/CACNA2D1/KCNJ2 Stable Cell Line-HEK293 | KCNJ2 | Human | Epithelial | INQUIRY |
Our products are only for research use. Not intended for any clinical or diagnostic use.
Inquiry