The human CACNA1C gene encodes the pore-forming subunits of Cav1.2. Inclusion of auxiliary subunits modulate gating and pharmacological properties, while the inwardly rectifying potassium channel allows the membrane potential to be altered with changes in extracellular K+. Cav1.2 channels expressed in heart, smooth muscle, neurons, and endocrine tissue are therapeutic targets in cardiac arrhythmia and hypertension.

Product Information
Catalog #:	ACC-RI0066
Gene Name	KCNJ2
Abbr	HEK293-HuCACNA1C/NEUROD1/CACNA2D1/KCNJ2
Alias	NEUROD1,BETA2,BHF 1,bHLHa3,MODY6,NeuroD,BHF-1,NEUROD
Growth Properties	Adherent
Host Cell	HEK293
Morphology	Epithelial
Shipping	Dry ice
Product Type	Ion Channel Expressing Cell
Channel Type	Calcium channel
Channel Subgroup	L-type channels
Species	Human
Product Format	frozen
searchKeyword	NEUROD1,BETA2,BHF 1,bHLHa3,MODY6,NeuroD,BHF-1,NEUROD

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