Kir2.1 has a fundamental role in controlling the resting potential of cardiac myocytes and shaping the cardiac action potential. It is therefore likely that drugs affecting this channel will have an effect on cardiac excitability. Mutations in the KCNJ2 gene that encodes Kir2.1, reduce expression of the channel and cause a form of long QT syndrome that predisposes individuals to ventricular arrhythmias. Recognition that the dysfunction of this channel can lead to long QT has lead to it's inclusion into the cardiac panel.

Product Information
Catalog #:	ACC-RI0024
Gene Name	KCNJ2
Abbr	HEK293-HuKCNJ2
Alias	NEUROD1,BETA2,BHF 1,bHLHa3,MODY6,NeuroD,BHF-1,NEUROD
Growth Properties	Adherent
Host Cell	HEK293
Morphology	Epithelial
Shipping	Dry ice
Product Type	Ion Channel Expressing Cell
Channel Type	Potassium Channel
Channel Subgroup	Inwardly rectifying (Kir)
Species	Human
Product Format	frozen
searchKeyword	NEUROD1,BETA2,BHF 1,bHLHa3,MODY6,NeuroD,BHF-1,NEUROD

Related Products

Catalog	Product Name	Gene Name	Species	Morphology	Price
ACC-RI0072	Human CACNA1A/AP4B1/CACNA2D1/KCNJ2 Stable Cell Line-HEK293	KCNJ2	Human	Epithelial	INQUIRY
ACC-RI0074	Human CACNA1B/BHLHE22/CACNA2D1/KCNJ2 Stable Cell Line-HEK293	KCNJ2	Human	Epithelial	INQUIRY
ACC-RI0080	Human CACNA1H/CACNB2/CACNA2D1/KCNJ2 Stable Cell Line-HEK293	KCNJ2	Human	Epithelial	INQUIRY
ACC-RI0116	Human KCNJ2 Stable Cell Line-CHO	KCNJ2	Human	Epithelial-like	INQUIRY
ACC-RI0115	Human KCNJ2 Stable Cell Line-HEK293	KCNJ2	Human	Epithelial	INQUIRY
ACC-RI0070	Human CACNA1D/CACNB3/CACNA2D1 + KCNJ2(tetracycline-inducible) Stable Cell Line-HEK293	KCNJ2	Human	Epithelial	INQUIRY
ACC-RI0066	Human CACNA1C/NEUROD1/CACNA2D1/KCNJ2 Stable Cell Line-HEK293	KCNJ2	Human	Epithelial	INQUIRY